Removal · field guidance

Lyme C6 peptide ELISA

The C6 ELISA targets a conserved peptide of VlsE and is FDA-cleared as a first- or second-tier test in the modified algorithm.

Steps

schema.org/HowTo

01
C6 ELISA detects antibodies to a 26-mer invariant region of the VlsE surface protein.
02
It is FDA-cleared as a stand-alone test and as a second tier in modified two-tier testing.
03
Sensitivity is comparable to whole-cell sonicate ELISA, with somewhat better specificity.
04
Useful in evaluating vaccinated dogs and cross-reactivity questions, since antigens differ.
05
Pair with a second EIA (modified two-tier) or with a Western blot per laboratory protocol.

loading…