Wild fact

Alpha Gal Cetuximab Discovery

Alpha-gal syndrome was discovered backwards. In the mid-2000s researchers including Thomas Platts-Mills and Scott Commins were trying to explain why some cancer patients reacted severely to the drug cetuximab. The shared antibody target turned out to be the alpha-gal sugar - and the geographic overlap with the lone star tick range pointed to the source of sensitization.

Related facts

6 facts · semantic similarity

Alpha Gal Only Allergy From Bite

Alpha-gal syndrome is the only known food allergy acquired from an arthropod bite. The lone star tick injects…

source · cdc.gov

Alpha Gal Delayed Reaction

The delayed-onset allergic reaction is what makes alpha-gal syndrome so easy to miss. Most food allergies trigger within minutes;…

source · cdc.gov

Lone Star Tick Vector Portfolio

A single tick species, Amblyomma americanum, transmits ehrlichiosis from Ehrlichia chaffeensis and E. ewingii, tularemia, Heartland virus,…

source · cdc.gov

Stari No Confirmed Pathogen

Southern tick-associated rash illness produces an expanding red rash that looks indistinguishable from early Lyme disease, but it follows…

source · aldf.com

Lone Star Tick Aggressive Quester

Amblyomma americanum, the lone star tick, is named for the single white spot on the female's scutum. Unlike Ixodes ticks, which sit and…

source · cdc.gov

Lone Star Not Cause of Lyme

Despite expanding overlap with Lyme disease in the southeastern United States, Amblyomma americanum (the lone star tick) does not transmit…

source · aldf.com