An FDA-approved Lyme vaccine for humans (LYMErix) was on the United States market from 1998 to 2002 before being withdrawn over weak demand and unproven safety concerns. As of 2026, no Lyme vaccine is licensed for humans in the United States; a candidate from Pfizer and Valneva is in late-phase trials. Veterinary Lyme vaccines for dogs remain widely used.
Unlike Lyme disease in the United States, tick-borne encephalitis has an effective inactivated-virus vaccine in routine use across central…
CDC's mandatory case reporting registers roughly 30,000 to 40,000 Lyme disease cases per year. Analysis of commercial insurance claims by…
A 2001 NEJM trial by Robert Nadelman and colleagues showed that a single 200 mg oral dose of doxycycline within 72 hours of removing an…
Roughly 95 percent of confirmed Lyme disease cases in the United States are reported from 14 high-incidence states clustered in the…
Lyme disease is named after Old Lyme, Connecticut, where in 1975 two mothers - Polly Murray and Judith Mensch - logged a cluster of…
Despite expanding overlap with Lyme disease in the southeastern United States, Amblyomma americanum (the lone star tick) does not transmit…