Ehrlichia chaffeensis and Anaplasma phagocytophilum cause clinically similar diseases but parasitize different white blood cells. Ehrlichia lives in monocytes (the disease was once called human monocytic ehrlichiosis); Anaplasma lives in neutrophils. Both are treated with doxycycline, but the cell type tells you which lab assay to order.
CDC's surveillance category undetermined ehrlichiosis or anaplasmosis exists because the two diseases share clinical presentation,…
Ehrlichia chaffeensis ehrlichiosis classically presents with fever, headache, and a triad of laboratory findings: leukopenia,…
When a clinician suspects ehrlichiosis or anaplasmosis but the antibody titers are too cross-reactive to call, PCR on whole blood drawn…
Anaplasma phagocytophilum lives inside human neutrophils, where it forms cytoplasmic clumps called morulae visible on a Giemsa-stained…
Ehrlichia ewingii ehrlichiosis was first recognized in human disease in 1999, almost exclusively in immunocompromised patients - HIV,…
Borrelia miyamotoi disease shares a vector with Lyme disease - the same Ixodes species - but presents differently: high fevers that recur…